%0 Journal Article %T Polymer Modified Carbon Paste Electrode as a Sensitive Sensor for the Electrochemical Determination of Riboflavin and Its Application in Pharmaceutical and Biological Samples %J Analytical and Bioanalytical Chemistry Research %I Iranian Chemical Society %Z 2383-093X %A Souza, Edwin S D’ %A Manjunatha, J.G. %A Raril, C. %A Tigari, Girish %A Pushpanjali, P. A. %D 2020 %\ 10/01/2020 %V 7 %N 4 %P 461-472 %! Polymer Modified Carbon Paste Electrode as a Sensitive Sensor for the Electrochemical Determination of Riboflavin and Its Application in Pharmaceutical and Biological Samples %K Riboflavin %K Electrochemical sensor %K Carbon paste electrode %K Poly (threonine) %K Ascorbic acid %K Folic acid %R 10.22036/abcr.2020.214882.1445 %X Poly (threonine) modified carbon paste electrode (PTMCPE) can be used as a responsive and selective electrocatalytic sensor for the estimation of riboflavin (RF) by means of cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The proposed electrode creates a catalytic enhancement in redox behavior of RF when equated with bare carbon paste electrode (BCPE). Under optimized conditions, RF quantification at modified electrode has shown a detection limit of 1.78×10-7 M in the linear range of 0.2-1 µM and 1-5 µM. Simultaneous analysis of RF with folic acid (FA) and ascorbic acid (AA) shows well-separated peaks leading to a quick and selective analysis of RF. The fabricated sensor can be successfully applied to RF analysis in human blood serum and B- complex tablet with acceptable results. Simultaneous analysis of RF with folic acid (FA) and ascorbic acid (AA) shows well-separated peaks leading to a quick and selective analysis of RF. The fabricated sensor can be successfully applied to RF analysis in human blood serum and B- complex tablet with acceptable results. %U https://www.analchemres.org/article_108072_6071cd996a9c85553f0cfb653baf3c65.pdf