Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
04
16
Nanomaterial Assisted Electrochemical Detection of Isolated Piperine: a Phytochemical From Long Pepper
209
217
EN
Khairunnisa
Amreen
Department of Chemistry-PG, St. Anns’ College for Women-Mehdipatnam, Hyderabad-500078, India
khairunnisa.amreen90@gmail.com
Sujatha
M
Department of Chemistry-PG, St. Anns’ College for Women-Mehdipatnam, Hyderabad-500078, India
sujatha.stanns09@gmail.com
10.22036/abcr.2021.253921.1548
Herein, Piperine, a phytochemical present in Long pepper is quantitatively analyzed via an electrochemical technique using a chemically modified electrode. Mesoporous nanomaterial has been utilized as a base matrix to carry out the experiments. The piperine is isolated from crude Long pepper through a standard procedure. Glassy carbon electrode is chemically modified with mesoporous carbon matrix and isolated piperine designated as (GCE/GMC@piperine). The cyclic voltammetry response gave a perfect redox response of piperine at E’= +0.2 V vs Ag/AgCl at 50 mV s-1in pH 7 PBS. Effect of scan rate and effect of solution pH was studied. Further, it was observed that a change in concentration of piperine is directly proportional to the redox peak current obtained. Therefore, this studies could act as a key for quantitative analysis of Piperine; naturally occurring phytochemical in natural products like Pepper, Long pepper, white pepper etc. This is a prototype study and can be further extended to disposable screen printed electrodes for portable analysis.
Piperine,Mesoporous carbon,quantitative,Long pepper,isolation
https://www.analchemres.org/article_129265.html
https://www.analchemres.org/article_129265_31bb25fe670def0ec4ab2d0c56b8d581.pdf
Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
04
16
PVA-based Pervaporation Membranes for Separation of Water-Alcohol Solutions: A Review
219
243
EN
Zohreh
Raeisi
Department of Chemistry, Dehloran Branch, Islamic Azad University, Dehloran, Iran
zohreh.eng84@gmail.com
Laleh
Hosseinzadeh
Department of Chemistry, Dehloran Branch, Islamic Azad University, Dehloran, Iran
l.hosseinzadeh2011@gmail.com
Ahmad
Moheb
Department of Chemical Engineering, Isfahan University of Technology, Isfahan 8415683111, Iran
ahmadmoheb1345@gmail.com
Morteza
Sadeghi
Department of Chemical Engineering, Isfahan University of Technology, Isfahan 8415683111, Iran
sadeghi.1358.m@gmail.com
10.22036/abcr.2021.236910.1519
Dehydration of alcohols has attracted a great deal of attention owing to its wide application in several medical, pharmaceutical and chemical industries. High separation efficiency, low energy consumption, simplicity and minimum contamination are the main characteristics which make pervaporation (PV) a promising method in the area of alcohol dehydration to provide extremely pure alcohols. Due to their permselectivity and high processability, polymers are the main materials for PV membranes. For this purpose, poly(vinyl alcohol) (PVA) is the most commonly used polymer because of its desired hydrophilicity, flexibility, good film-forming ability and low cost. However, excessive swelling is the main challenge in fabrication of PVA membranes for dehydration application; to overcome this disadvantage, various attempts have been made to modify PVA membranes for separation of water and alcohols. In this paper, various modifications and developments that have been made to improve the PV performance of PVA-based membranes for separation of water and alcohols have been reviewed.
Separation,Alcohols,Poly(vinyl alcohol),Membrane,dehydration
https://www.analchemres.org/article_129266.html
https://www.analchemres.org/article_129266_f1597780605490323faa29511c6d8341.pdf
Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
07
01
Voltammetric Determination of Sumatriptan by an Overoxidized Poly(p-aminophenol) Modified Glassy Carbon Electrode
245
259
EN
Mohammad Reza
Jalali-Sarvestani
Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran
m.jalalisarvestani@che.basu.ac.ir
Tayyebeh
Madrakian
0000-0002-6876-7633
Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran
madrakian@basu.ac.ir
Abbas
Afkhami
0000-0002-3559-2080
Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran. D-8 International University, Hamedan, Iran
afkhami@basu.ac.ir
10.22036/abcr.2021.259273.1558
This study aims to develop a promising electrochemical sensor based on polymer film overoxidation following the electrochemical polymerization of p-aminophenol on a bare glassy carbon electrode (GCE) surface for the voltammetric determination of sumatriptan succinate (SUM). Cyclic voltammetry (CV), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and square wave voltammetry (SWV) were employed to characterize the electroanalytical performance and morphology of the modified electrode. The results indicated a significant improvement in electrode sensitivity to SUM after electrochemical polymerization and overoxidation of poly(p-aminophenol). We also investigated the effect of all effective instrumental and experimental parameters on sensor response. Under the optimum conditions (accumulation for 60 s at 0.055V and pH= 2.0) the electrode SWV response to SUM within the range 1.0-100.0 μmol L-1 with a limit of detection (LOD) of 0.294 μmol L-1 was linear under optimized conditions. We also attempted to evaluate the designed sensor selectivity to different interfering species, suggesting no significant interference. The designed sensor was also used to determine SUM in pharmaceutical preparations and human serum samples with minimal matrix effects, admissible recoveries (99-106), and satisfactory repeatability (1.2-5.1 %RSD). The proposed sensor exhibited admissible repeatability, reproducibility, and stability.
Sumatriptan,Square wave voltammetry,Poly(4-aminophenol),glassy carbon electrode
https://www.analchemres.org/article_129267.html
https://www.analchemres.org/article_129267_a2a934e4b3f8ce0e33e912256b1c2a66.pdf
Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
07
01
Electrochemical Sensing of Folic Acid in Presence of Ascorbic acid Using Carbon Paste Nano Composite Modified Electrode
261
274
EN
Masoud Reza
Shishehbore
Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran
shishehboreazaduni@gmail.com
Shohreh
Vafaee-Shahi
Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran
svafaee57@gmail.com
Ali
Sheibani
0000-0003-4053-8908
Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran
alisheibani@ymail.com
Masoumeh
Tabatabaee
Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran
tabatabaee45@gmail.com
10.22036/abcr.2021.260921.1562
In the present work, combination of unique properties of two nano material compounds, MgO nano paricles (MgO NPs) and multi-wall carbon nanotubes (MWCNT), and electrocatalytic activity of an oxadiazole derivative, 3-(5-(pyridine-4-yl)-1,3,4-oxadiazole-2-ylthio)-4- methylcyclohexa-1,3-diene-1,2-diol; POM, was used to fabricate a sensitive electrode (POM-MgO NPs-MWCNT-CPE) for electrochemical determination of folic acid. The electrochemical treatment of folic acid was studied in phosphate buffer solution (0.1 M, pH 7) by means of common electrochemical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The sensitive fabricated electrode displayed good operating characteristics such as wide linear range and low detection limit for the determination of folic acid. Using the fabricated electrode, a wide linear dynamic range in concentration range 0.08-650.0 μM, and a limit of detection of 0.02 μM were found. Using the modified electrode, the two well distinguished peaks were recorded at 110.0 and 209 mV for ascorbic acid and folic acid, respectively. Reliability and accuracy of the introduced electrode were studied in pharmaceutical and biological samples.
Carbon paste electrode,Oxadiazole derivative,Multiwall carbon nanotubes,Folic acid,Ascorbic acid
https://www.analchemres.org/article_130413.html
https://www.analchemres.org/article_130413_5db36718469650ce9417f4eefffbd70e.pdf
Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
07
01
Aptamer-based Electrochemical Detection of Tyrosinamide Using Metal-organic Frameworks/silver Nanoparticles Modified Glassy Carbon Electrode
275
283
EN
Kazhal
Ghanbari
Department of Chemistry, Faculty of Sciences, Ilam University, Ilam, Iran
ghanbarikajal@yahoo.com
Mahmoud
Roushani
0000-0001-6749-5878
Department of Chemistry, Faculty of Sciences, Ilam University, Ilam, Iran
mahmoudroushani@yahoo.com
Azadeh
Azadbakht
Department of Chemistry, Khorramabad Branch Islamic Azad University Khorramabad, Iran
azadeh_azadbakht@yahoo.com
10.22036/abcr.2021.261628.1566
In this report, a new aptamer-based assay was presented reporting the electrochemical aptasensing for sensing tyrosinamide (Tyr-NH2). This strategy was relied on unbeatable conformational flexibility and specific recognition of aptamers. The tyrosinamide aptamer (Tyr-NH2-aptamer) was immobilized onto the metal-organic frameworks/silver nanoparticles modified glassy carbon electrode and hexacyanoferrate was selected as a probe to monitor interface variations during modification of the electrode and the aptamer conformational change generated by the Tyr-NH2 binding. Results showed that measurements by using electrochemical impedance spectroscopy had linear with the Tyr-NH2 concentrations in range of 0.01-0.25 nM and 0.25-1.15 nM. Detection limit of this system was found to be 2.3 pM. This method was also used to the Tyr-NH2 detection in serum samples successfully. Remarkable simplicity, ease of use and low-cost, make methodology as sensitive analytical system for sensing of the Tyr-NH2 that can be miniaturized. This strategy offers some promising advantages in reliable detection of the Tyr-NH2, which may be helpful in the routine analysis.
Electrochemical aptasensor,Tyrosinaimde,Hexacyanoferrate,Metal-organic Frameworks,Silver nanoparticls
https://www.analchemres.org/article_130116.html
https://www.analchemres.org/article_130116_5a6fc42f8b669b6ee0ba4031e667c1d4.pdf
Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
07
01
Fabrication and Characterization of the Green Synthesized Magnetic Chitosan-zinc Nanocomposites: A Reusable and Effective Multifunctional Nanocatalyst for the Reduction of Organic Pollutants
385
403
EN
Masoumeh
Masoudinia
Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran
masoudinia@gmail.com
Arastoo
Badoei-dalfard
https://orcid.org/0000-0002-9266-057X
Department of Biology, Faculty of sciences, Shahid Bahonar university of Kerman, Kerman, Iran
badoei@uk.ac.ir
Hadi
Ravan
Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran
rawan@gmail.com
Zahra
Karami
https://orcid.org/0000-0003-2269-8107
Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran
karami@uk.ac.ir
10.22036/abcr.2021.258803.1554
Bimetallic nanoparticles have numerous applications in different areas, including catalysis, medicine, optics, and so on. Due to numerous intrinsic disadvantages and potentially toxic chemical procedures, finding nontoxic, green, cost-effective, and eco-friendly approaches for the production of bimetallic nanoparticles is much desired. In this study, Zn NPs, Zn/Fe3O4 NPs, and Zn/Chitosan/Fe3O4 nanocomposites were synthesized via a one-pot procedure by using leave extract of Quercus brantii, in the absence of any dangerous components. The catalytic capacity of the green synthesized Zn/Chitosan/Fe3O4 nanocomposite was considered for the degradation of environmental pollutants, including Congo red (CR), Methylene blue (MB), Cr(VI), and 4-nitrophenol (4-NP). The Zn/Chitosan/Fe3O4 nanocomposites have been morphologically characterized using UV–Vis, SEM, and EDX studies. The antioxidant reducing and antibacterial activities of Zn/Chitosan/Fe3O4 nanocomposites have been considered. Our results showed that this nanocomposite could be reused five times for removal of Congo red (CR), Methylene blue (MB), Cr(VI), and four times for reduction of 4-nitrophenol (4-NP), without substantial reduction in the catalytic capacity. Results showed the high potential catalytic activity of Zn/Chitosan/Fe3O4 nanocomposite for the reduction of organic pollutants.
Magnetic Chitosan,Bimetallic nanoparticles,Zn/Chitosan/Fe3O4 nanocomposite,Catalytic reduction,4-Nitrophenol,Congo red
https://www.analchemres.org/article_130120.html
https://www.analchemres.org/article_130120_371393dd725bc2637196dc6edfbe5492.pdf
Iranian Chemical Society
Analytical and Bioanalytical Chemistry Research
2383-093X
8
3
2021
07
01
A Simple Liquid Chromatographic Method for Estimation of Glycopyrrolate in Pharmaceuticals Using Experimental Design
405
415
EN
Sagar Suman
Panda
0000-0002-9138-5561
Department of Pharmaceutical Analysis & Quality Assurance, Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha, India
sagarguddu2002@gmail.com
Ravi kumar
Venkata Varaha
Bera
Department of Pharmaceutical Analysis & Quality Assurance, Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha, India
ravikumar_bvv@yahoo.co.uk
Raja kumar
Viriyala
Grapes College of Pharmacy, Koyyalagudem, Andhra Pradesh, India
vrkdr@yahoo.com
Suman
Kumar
Mekap
Centurion University of Technology & Management, Khurda, Odisha, India.
sumanmpharm@gmail.com
10.22036/abcr.2021.228784.1489
A liquid chromatographic method was developed and validated to estimate glycopyrrolate (GLP) present in pharmaceutical formulations. The method was developed using a C18 column with a mobile phase involved methanol: phosphate buffer (pH=3.2) (65:35, %v/v) flowing at 1.0ml min-1. GLP was detected at a wavelength of 224nm. The method was found linear over a concentration range of 6-14µg ml-1. Degradation studies proved the chromatographic method specificity. Validation studies postulated method acceptability and suitability for estimating GLP in both bulk as well as injectables. The detection and quantitation limits were 2.5µg ml-1 and 6.0µg ml-1, respectively. Further, method precision was assured (%R.S.D. <2%) employing an experimental design approach using a factorial design. Also, it revealed that analyst skills are of critical importance and may influence the method preciseness. Overall the method was reliable and of optimum quality and possesses the potential of application in routine quality control of dosage forms of GLP and may serve as a basis for future bio-analytical method development purpose.
Anticholinergic,Factorial design,Injectables,Stability-indicating,Validation
https://www.analchemres.org/article_131052.html
https://www.analchemres.org/article_131052_92ee270851cd77f9ebb667db7c98f32c.pdf