Nanomaterial Assisted Electrochemical Detection of Isolated Piperine: a Phytochemical From Long Pepper

Document Type : Research Paper

Authors

Department of Chemistry-PG, St. Anns’ College for Women-Mehdipatnam, Hyderabad-500078, India

10.22036/abcr.2021.253921.1548

Abstract

Herein, Piperine, a phytochemical present in Long pepper is quantitatively analyzed via an electrochemical technique using a chemically modified electrode. Mesoporous nanomaterial has been utilized as a base matrix to carry out the experiments. The piperine is isolated from crude Long pepper through a standard procedure. Glassy carbon electrode is chemically modified with mesoporous carbon matrix and isolated piperine designated as (GCE/GMC@piperine). The cyclic voltammetry response gave a perfect redox response of piperine at E’= +0.2 V vs Ag/AgCl at 50 mV s-1in pH 7 PBS. Effect of scan rate and effect of solution pH was studied. Further, it was observed that a change in concentration of piperine is directly proportional to the redox peak current obtained. Therefore, this studies could act as a key for quantitative analysis of Piperine; naturally occurring phytochemical in natural products like Pepper, Long pepper, white pepper etc. This is a prototype study and can be further extended to disposable screen printed electrodes for portable analysis.

Keywords


[1]       P.S. Ved, S. Utkarsh, C. Mahadev, V.N. Shukla, 5 (2018) 6376.
[2]       R. Hindumathi, M. Jagannatham, P. Haridoss, C. P. Sharma, Nano Strutures and Nano Objects 13 (2018) 30.
[3]       S.S. Magendran, F.S.A. Khan, N.M. Mubarak, M. Vaka, R. Walvekar, M. Khalid, E.C. Abdullah, S. Nizamuddin, R.R. Karri, Nano Structures and Nano Objects 20 (2019) 100399.
 
 
[4]       H. K. Ja, S. Jungmok, L. Taeyoon, Thin Solid Films 5 (2012) 1.
[5]       A. Mathiazhagan, J.  Rani, Int. J. Chem. Eng. 2 (2011) 225.
[6]       A. Amania, M. Salehib, M. Jamshidi, Anal. Bioanal. Chem. Res. 7 (2020) 541.
[7]       C. Aicheng, C. Sanghamitra, Chem. Soc. Rev. 42 (2013) 5425.
[8]       M.M. Ardakani, M. Yavari, A. Khoshroo, Anal. Bioanal. Chem. Res. 6 (2019) 183.
[9]       J.V. Peter, R.W. Krista, Environ. Sci. Technol.  44 (2010) 3656.
[10]    F.R. James, S. Gregory, P. Fotios, Bioelectrochemistry 76 (2009) 189.
[11]    Z. Dehghania, S. Dadfarniaa, A.M.H. Shabania, M.H. Ehrampoush, Anal. Bioanal. Chem. Res. 7 (2020) 509. 
[12]    R.K. Janardhan, K.K. Suresh, R.B. Jigna, K. Ki-Hyun, D. Tanushree, V. Kowsalya, Adv. Colloid Interface Sci. 256 (2018) 326.
[13]    C. Hwei-Jay, L. Chi-Young, T. Nyan-Hwa, Carbon 80 (2014) 725.
[14]    K. Amreen, V.K. Shukla, S. Shukla, D. Rajagopalan, A.S. Kumar, Nano Strucutres and Nano Objects 11 (2017) 56.
[15]    E. Antonio, A. Anna, V. Maurizio, C.Z. Maria, Phytochem. Anal. 12 (2001) 383.
[16]    K. Duduku, S. Rosalam, B. Awang, Biotechnol. Mol. Biol. Rev. 1 (2007) 97.
[17]    L. Claus, Forsch Komplementmed 23 (2016) 69.
[18]    C. Anoma, J.K. Thamilini, Int. J. Food Sci. (2016).
[19]    K.M. Pulok, K.N. Neelesh, M.  Niladri, K.S. Birendra, Fitoterapia 84 (2013) 227.
[20]    H.R. Arshad, A.A. Mohammed, M.A. Salah, A.K.  Masood,  H.A.  Yousef,  Adv.  Biomed.  Res. 7 (2018)  
 
 
 
 
 
 
 
 
 
 
 
 
38.
[21]    C.L. Gopu, A. Suyog, M. Hiral, A.R. Paradkar, K.R. Mahadik, Phytochem. Anal. 19 (2008) 116.
[22]    M. Sunita, D. Sukriti, H. Saikat, L. Mohan, J. Essent. Oil Bear. Pl. 21 (2018) 994.
[23]    P.G. Van, Eur. J. Clin. Nutr. 50 (1996) 57.
[24]    K.S. Surinder, S.V. Amarji, S. Mohit,Eur. J. Pharmacol. 720 (2013) 55.
[25]    M. Peyman, M. Surush, M. Milad, A. Shahin, S. Shadi, Iran. J. Basic Med. Sci. 16 (2013) 1031.
[26]    Q.P. Yin, Epilepsia 24 (1983) 177.
[27]    G. Leila, M. Maedeh, D.N. Ghasem, N. Maryam, Compr. Rev. Food Sci. Food Saf. 16 (2017) 124.
[28]    K.N. Babu, M. Divakaran, P.N. Ravindran, K.V. Peter, Hand Book of Herbs and Spices.
[29]    M. Murlidhar, T.K. Goswami, Phytother. Res. 27 (2013) 1121.
[30]    P. Subramani, S.T. Gan, A.D. Sokkalingam, Pharmacogn. Rev. 8 (2014) 73.
[31]    T. Rajendiran, A.S. Kumar, Anal. Methods 4 (2012) 2162.
[32]    Y. Xiaofeng, G. Miaomiao, H. Haidong, Z. Huajie, Phytochem. Anal. 22 (2011) 291.
[33]    C.T. Gerardo, D.C. Antonio, F. Bruno, P. Erwan, F. Alain, Phytochem. Anal. 28 (2017) 171.
[34]    W. Yuanzhe, C. Lifu, C. Korbua, G.C. Richard, Food Chem. 309 (2020) 125606.
[35]    P.N. Shingate, P.N. Dongre, D.M. Kannur, Int. J. Pharm. Sci. Res. 4 (2013) 3165.
[36]     C.R. Quijia, M. Chorilli, Acta Pharm. 71 (2021).
[37]    A.S. Kumar, R. Shanmugam, N. Vishnu, K.C. Pillai, S. Kamaraj, J. Electroanal. Chem. 782 (2016) 215.
[38]    P. Barathi, A.S. Kumar, Electrochim. Acta 135 (2014) 1.