@article { author = {Garkani, Fariba and Beitollahi, Hadi and Tajik, Somayeh and Jahani, Shohreh}, title = {La3+-doped Co3O4 Nanoflowers Modified Graphite Screen Printed Electrode for Electrochemical Sensing of Vitamin B6}, journal = {Analytical and Bioanalytical Chemistry Research}, volume = {6}, number = {1}, pages = {69-79}, year = {2019}, publisher = {Iranian Chemical Society}, issn = {2383-093X}, eissn = {2383-093X}, doi = {10.22036/abcr.2018.134444.1212}, abstract = {In this study, we combined the advantages of good conductivity, small size, and large surface area and the catalytic property of La3+/Co3O4 nanoflowers to fabricate an electrochemical sensor sensitive to determination of vitamin B6 in real samples. La3+/Co3O4 nanoflowers were synthesized by a co-precipitation method which is a convenient, environment-friendly, inexpensive process. The synthesized nanoflowers were characterized by SEM. A simple and sensitive sensor based on graphite screen printed electrode (GSPE) modified by La3+/Co3O4 nanoflowers was developed for the electrochemical determination of vitamin B6. The electrochemical behavior of vitamin B6 was studied in 0.1 M phosphate buffer solution (PBS) using cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV). The modified electrode (La3+/Co3O4NFs/GSPE) showed excellent electrocatalytic activity and remarkable sensitivity towards the oxidation of vitamin B6. The fabricated sensor displayed good operating characteristics including low detection limit, and a wide linear dynamic range for the detection of vitamin B6. Using La3+/Co3O4NFs/GSPE as the working electrode, a linear dynamic range between 1.0 to 600.0 μM and a limit of detection of 0.4 µM were obtained. Finally, reliability and accuracy of the proposed sensor were studied in real samples.}, keywords = {La3+/Co3O4 Nanoflowers,Electrochemical sensor,Vitamin B6,Real samples,Modified electrode}, url = {https://www.analchemres.org/article_69523.html}, eprint = {https://www.analchemres.org/article_69523_53caaa7d46fd1013cebc6270a48bf3c0.pdf} }