TY - JOUR ID - 50854 TI - Voltammetric Determination of Tryptophan Using a Carbon Paste Electrode Modified with Magnesium Core Shell Nanocomposite and Ionic Liquids JO - Analytical and Bioanalytical Chemistry Research JA - ABCR LA - en SN - AU - Mohammadi, Sayed Zia AU - Beitollahi, Hadi AU - Hassanzadeh, Mohsen AD - Payame Noor University AD - aEnvironment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran AD - Department of Chemistry, Payamenoor University, Bam, Iran Y1 - 2018 PY - 2018 VL - 5 IS - 1 SP - 55 EP - 65 KW - tryptophan KW - Magnetic core-shell manganese ferrite nanoparticles KW - Ionic Liquids KW - Chemically modified electrodes DO - 10.22036/abcr.2017.88326.1149 N2 - A novel carbon paste electrode modified with ionic liquid (n-hexyl-3-methylimidazolium hexafluoro phosphate) and magnetic core-shell manganese ferrite nanoparticles (MCSILCPE) was fabricated. The electrochemical study of the modified electrode, as well as its efficiency for electro-oxidation of tryptophan, is described. Cyclic voltammetry (CV), choronoamperometry (CHA) and square wave voltammetry (SWV) were used to investigate oxidation of tryptophan in aqueous solution. The diffusion coefficient (D=3.53 ×10-6 cm2/s), was determined using electrochemical approaches. It has been found that under an optimum condition (pH 7.0), the oxidation of tryptophan at the surface of such an electrode occurs at a potential about 150 mV less positive than that of an unmodified carbon paste electrode. SWV exhibits a linear dynamic range from 5.0×10-6 to 4.0×10−4 M tryptophan. The morphology of the modified electrode was studied using SEM. The limit of detection was equal to 1.1×10-6 M. The electrode was also employed to determination of tryptophan in urine samples. UR - https://www.analchemres.org/article_50854.html L1 - https://www.analchemres.org/article_50854_1d19a500c075c0c5c9fb135907f04f7d.pdf ER -