Polymer Modified Carbon Paste Electrode as a Sensitive Sensor for the Electrochemical Determination of Riboflavin and Its Application in Pharmaceutical and Biological Samples

Document Type: Research Paper

Authors

Department of Chemistry, FMKMC College, Madikeri, Mangalore University Constitue

10.22036/abcr.2020.214882.1445

Abstract

Poly (threonine) modified carbon paste electrode (PTMCPE) can be used as a responsive and selective electrocatalytic sensor for the estimation of riboflavin (RF) by means of cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The proposed electrode creates a catalytic enhancement in redox behavior of RF when equated with bare carbon paste electrode (BCPE). Under optimized conditions, RF quantification at modified electrode has shown a detection limit of 1.78×10-7 M in the linear range of 0.2-1 µM and 1-5 µM. Simultaneous analysis of RF with folic acid (FA) and ascorbic acid (AA) shows well-separated peaks leading to a quick and selective analysis of RF. The fabricated sensor can be successfully applied to RF analysis in human blood serum and B- complex tablet with acceptable results. Simultaneous analysis of RF with folic acid (FA) and ascorbic acid (AA) shows well-separated peaks leading to a quick and selective analysis of RF. The fabricated sensor can be successfully applied to RF analysis in human blood serum and B- complex tablet with acceptable results.

Keywords


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