A Copper-Based Metal-Organic Framework/Molecularly Imprinted Polymer-Modified Graphite Epoxy Composite Electrode for the Electrochemical Detection of Chlorpyrifos and Investigating Optimum Conditions with the aid of Quantum-Mechanical DFT Calculations

Document Type : Research Paper

Authors

Department of Chemistry, Faculty of Sciences, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran

Abstract

In this study, a new electrochemical sensor using MIPs coated on the surface of Cu-MOF was developed for the selective determination of chlorpyrifos (CPF). Cu-MOF (HKUST-1) was synthesized based on a solvothermal method. Molecularly imprinted polymers (MIPs) were prepared using chlorpyrifos as the template molecule, methacrylic acid as the functional monomer, and ethylene glycol dimethyacrylate as the cross-linker. The optimum pH value of the rebinding solution was verified with computational calculations obtained by Gaussian software. The HKUST-1 @MIP was characterized by several technique include, Fourier-transform infrared spectroscopy (FT-IR), field-emission scanning electron microscopy (FESEM), and X-ray diffraction (XRD). HKUST-1 @MIP/GEC electrode showed an excellent linear range of 0.01 to 1.00 µM, with RSD% and LOD of 5.37% and 3 nM, respectively. The modified electrode presents a simple, selective, sensitive, stable and environmentally friendly strategy for the determination of CPF. The proposed method was successfully used to measure CPF in apple and tomato samples.

Keywords

Analytical and Bioanalytical Chemistry Research
Volume 10, Issue 3
July 2023
Pages 363-373

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